Non-local validated parametrization of an agent-based model of local-scale Taenia solium transmission in North-West Peru.

ABSTRACT: The pork tapeworm, Taenia solium, is the cause of a preventable zoonotic disease, cysticercosis, affecting both pigs and humans. Continued endemic transmission of T. solium is a major contributor of epilepsy and other neurologic morbidity, and the source of important economic losses, in many rural areas of developing countries. Simulation modelling can play an important role in aiding the design and evaluation of strategies to control or even eliminate transmission of the parasite. In this paper, we present a new agent based model of local-scale T. solium transmission and a new, non-local, approach to the model calibration to fit model outputs to observed human taeniasis and pig cysticercosis prevalence simultaneously for several endemic villages. The model fully describes all relevant asp

SUBMITTER: Pizzitutti F 

PROVIDER: S-EPMC9514638 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature