Mucoepidermoid carcinoma (MEC) and adenosquamous carcinoma (ASC), the same or different entities?

ABSTRACT: Mucoepidermoid carcinoma (MEC) and adenosquamous carcinoma (ASC) have overlapping histopathological appearances and sites of occurrence, which may cause diagnostic difficulty impacting subsequent treatment. We conducted a systematic review of the scientific literature to determine whether molecular alterations were sufficiently different in MEC and ASC to aid in classifying the two entities. We searched Medline, Embase and Web of Science for studies reporting molecular determinations of ASC and/or MEC and screened retrieved records for eligibility. Two independent researchers reviewed included studies, assessed methodological quality and extracted data. Of 8623 identified records, 128 articles were included for analysis: 5 which compared the two tumors in the same investigation using the s

SUBMITTER: White VA 

PROVIDER: S-EPMC9514988 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature