Brain PET motion correction using 3D face-shape model: the first clinical study.

ABSTRACT:

Objective

Head motions during brain PET scan cause degradation of brain images, but head fixation or external-maker attachment become burdensome on patients. Therefore, we have developed a motion correction method that uses a 3D face-shape model generated by a range-sensing camera (Kinect) and by CT images. We have successfully corrected the PET images of a moving mannequin-head phantom containing radioactivity. Here, we conducted a volunteer study to verify the effectiveness of our method for clinical data.

Methods

Eight healthy men volunteers aged 22-45 years underwent a 10-min head-fixed PET scan as a standard of truth in this study, which was started 45 min after ¹⁸F-fluorodeoxyglucose (285 ± 23 MBq) injection, and followed by a 15-min head-moving PET scan wit

SUBMITTER: Iwao Y 

PROVIDER: S-EPMC9515015 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature