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Dipotassium 1,3,4-thiadiazole-2,5-bis(thiolate) as a new S-donor for direct synthesis of symmetrical disulfides.

ABSTRACT: In this research, a simple, efficient and novel protocol is eveloped for the direct synthesis of symmetrical disulfides using dipotassium 1,3,4-thiadiazole-2,5-bis(thiolate) as a new, low toxicity, inexpensive, stable solid and free of foul-smelling thiols for synthesize symmetric diaryl/dialkyl disulfides from aryl and alkyl halides in presence of MOF-199 and CuO nanoparticles. Significantly, using this method results in obtaining a variety of symmetrical disulfides in moderate to excellent yields (up to 98%).

SUBMITTER: Soleiman-Beigi M

PROVIDER: S-EPMC9515069 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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Dipotassium 1,3,4-thiadiazole-2,5-bis(thiolate) as a new S-donor for direct synthesis of symmetrical disulfides.

Soleiman-Beigi Mohammad M Alikarami Mohammad M Kohzadi Homa H Akbari Zahra Z

Scientific reports 20220927 1

In this research, a simple, efficient and novel protocol is eveloped for the direct synthesis of symmetrical disulfides using dipotassium 1,3,4-thiadiazole-2,5-bis(thiolate) as a new, low toxicity, inexpensive, stable solid and free of foul-smelling thiols for synthesize symmetric diaryl/dialkyl disulfides from aryl and alkyl halides in presence of MOF-199 and CuO nanoparticles. Significantly, using this method results in obtaining a variety of symmetrical disulfides in moderate to excellent yie ...[more]

PMID: 36167798

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