A computational comparison of radiofrequency and pulsed field ablation in terms of lesion morphology in the cardiac chamber.

ABSTRACT: Pulsed Field Ablation (PFA) has been developed over the last years as a novel electrical ablation technique for treating cardiac arrhythmias. It is based on irreversible electroporation which is a non-thermal phenomenon innocuous to the extracellular matrix and, because of that, PFA is considered to be safer than the reference technique, Radiofrequency Ablation (RFA). However, possible differences in lesion morphology between both techniques have been poorly studied. Simulations including electric, thermal and fluid physics were performed in a simplified model of the cardiac chamber which, in essence, consisted of a slab of myocardium with blood in motion on the top. Monopolar and bipolar catheter configurations were studied. Different blood velocities and catheter orientations were assaye

SUBMITTER: Gomez-Barea M 

PROVIDER: S-EPMC9515184 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature