Dataset Information
Fragile X-associated tremor ataxia syndrome rating scale: Revision and content validity using a mixed method approach.
Ontology highlight
ABSTRACT: Background
The original Fragile X-associated Tremor Ataxia Syndrome Rating Scale (FXTAS-RS) contained 61 items, some requiring modifications to better meet recommendations for patient-focused rating scale development.Purpose
Provide initial validation of a revised version of the FXTAS-RS for motor signs.Method
We conducted a two-phase mixed-method approach. In Phase 1, revision, we implemented a Delphi technique identifying pertinent domains/subdomains and developing items through expert consensus. In Phase 2, content validation, we conducted cognitive pretesting assessing comprehensibility, comprehensiveness, and relevance of items to FXTAS motor signs.Results
After five rounds of Delphi panel and two rounds of cognitive pretesting, the revised version of the FXTAS-RS was established with 18 items covering five domains and 13 subdomains of motor signs. Cognitive pretesting revealed adequate content validity for the assessment of FXTAS motor signs.Conclusion
The revised FXTAS-RS has been successfully validated for content and it is now ready for large-scale field validation.
SUBMITTER: Tosin MHS
PROVIDER: S-EPMC9515309 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Publications
Fragile X-associated tremor ataxia syndrome rating scale: Revision and content validity using a mixed method approach.
Frontiers in neurology 20220914
<h4>Background</h4>The original Fragile X-associated Tremor Ataxia Syndrome Rating Scale (FXTAS-RS) contained 61 items, some requiring modifications to better meet recommendations for patient-focused rating scale development.<h4>Purpose</h4>Provide initial validation of a revised version of the FXTAS-RS for motor signs.<h4>Method</h4>We conducted a two-phase mixed-method approach. In Phase 1, revision, we implemented a Delphi technique identifying pertinent domains/subdomains and developing item ...[more]