Anodal transcranial direct current stimulation sustainably increases EEG alpha activity in patients with schizophrenia.

ABSTRACT:

Aims

Transcranial direct current stimulation (tDCS) applied to the prefrontal cortex has been frequently used to elicit behavioral changes in patients with schizophrenia. However, the interaction between prefrontal tDCS and electrophysiological changes remains largely uncharted. The present study aimed to investigate cortical electrophysiological changes induced by tDCS in frontal areas by means of repeated electroencephalography (EEG) in patients with schizophrenia.

Methods

In total, 20 patients with schizophrenia received 13 minutes of anodal tDCS (1 mA) applied to the left dorsolateral prefrontal cortex (DLPFC). Repeated resting EEG was recorded before (once) and following (at five follow-up time-bins) tDCS to trace post-tDCS effects. We used sLORETA for source reconstruc

SUBMITTER: Pross B 

PROVIDER: S-EPMC9515721 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature