TNAP-a potential cytokine in the cerebral inflammation in spastic cerebral palsy.

ABSTRACT: Objective: Several studies have shown the significance of neuroinflammation in the pathological progress of cerebral palsy (CP). However, the etiology of CP remains poorly understood. Spastic CP is the most common form of CP, comprising 80% of all cases. Therefore, identifying the specific factors may serve to understand the etiology of spastic CP. Our research aimed to find some relevant factors through protein profiling, screening, and validation to help understand the pathogenesis of cerebral palsy. Materials and methods: In the current study, related clinical parameters were assessed in 18 children with spastic CP along with 20 healthy individuals of the same age. Blood samples of the spastic CP children and controls were analyzed with proteomics profiling to detect diffe

SUBMITTER: Wang XK 

PROVIDER: S-EPMC9515907 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature