Liver blood marker testing in UK primary care: a UK wide cohort study, 2004-2016.

ABSTRACT:

Objective

We aimed to determine (1) the temporal trends of liver enzyme testing in UK general practice and (2) how these vary among different subgroups at risk of chronic liver disease (CLD).

Design

Retrospective cohort study.

Setting

UK primary care database (Clinical Practice Research Datalink (CPRD)), 2004-2016.

Participants

Patients aged 18 years or over, registered in the CPRD from 1 January 2004 to 31 December 2016.

Outcome measures

The frequency of testing recorded within the study period in general practice was calculated for: alanine aminotransferase (ALT); aspartate aminotransferase (AST); gamma glutamyl transferase (GGT); alkaline phosphatase (ALP); bilirubin and platelets. Analyses were conducted in subgroups of patients at high risk of devel

SUBMITTER: Scutt P 

PROVIDER: S-EPMC9516205 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature