Effectiveness of screening for oral cancer and oral potentially malignant disorders (OPMD): A systematic review

ABSTRACT: Oral cancer (OC) is a debilitating disease with a high mortality rate when diagnosed in advanced stage. Conversely, early-stage OC has a high survival rate, supporting a need for early detection programmes. A previous systematic review of clinical trials evaluating efficacy of screening for OC was inconclusive. This systematic review aimed to determine the impact of screening for oral lesions on reducing mortality and incidence of OC by looking at a broader spectrum of evidence. The search for randomized controlled trials and observational studies with a control group was conducted in PubMed, OVID, Cochrane, CINAHL and grey literature sources. Risk of bias for included studies was assessed with the tools developed by the Cochrane collaboration. Six out of two identified randomized trials a

SUBMITTER: Parak U 

PROVIDER: S-EPMC9516446 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature