Examining the role of systemic chronic inflammation in diet and sleep relationship.

ABSTRACT:

Background

It is well known that systemic chronic inflammation (SCI), which can be modulated by diet, is associated with poor sleep outcomes. However, the role of SCI in diet health and sleep quality relationship has not been well established.

Methods

Here, by using the UK Biobank data set, we assessed the association between markers of SCI (leukocyte, platelet, lymphocyte, neutrophil, and basophil counts; C-reactive protein levels and neutrophil to lymphocyte ratio (NLR)), habitual intake of food groups, diet health and sleep quality in 449,084 participants. We also formally tested the possibility that SCI might mediate the relationship between diet health and sleep quality.

Results

Our results revealed (i) negative associations between SCI and food groups that are a

SUBMITTER: Hepsomali P 

PROVIDER: S-EPMC9516605 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature