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Isophthalate:coenzyme A ligase initiates anaerobic degradation of xenobiotic isophthalate.


ABSTRACT:

Background

Environmental contamination from synthetic plastics and their additives is a widespread problem. Phthalate esters are a class of refractory synthetic organic compounds which are widely used in plastics, coatings, and for several industrial applications such as packaging, pharmaceuticals, and/or paints. They are released into the environment during production, use and disposal, and some of them are potential mutagens and carcinogens. Isophthalate (1,3-benzenedicarboxylic acid) is a synthetic chemical that is globally produced at a million-ton scale for industrial applications and is considered a priority pollutant. Here we describe the biochemical characterization of an enzyme involved in anaerobic degradation of isophthalate by the syntrophically fermenting bacterium Syn

SUBMITTER: Junghare M 

PROVIDER: S-EPMC9516798 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature