Comorbidities and mortality risk in adults younger than 50 years of age with chronic obstructive pulmonary disease.

ABSTRACT:

Rationale and objective

Patients with chronic obstructive pulmonary disease (COPD), usually diagnosed after the 6th decade, frequently suffer from comorbidities. Whether COPD patients 50 years or younger (Young COPD) have similar comorbidities with the same frequency and mortality impact as aged-matched controls or older COPD patients is unknown.

Methods

We compared comorbidity number, prevalence and type in 3 groups of individuals with ≥ 10 pack-years of smoking: A Young (≤ 50 years) COPD group (n = 160), an age-balanced control group without airflow obstruction (n = 125), and Old (> 50 years) COPD group (n = 1860). We also compared survival between the young COPD and control subjects. Using Cox proportional model, we determined the comorbidities associated with mortality r

SUBMITTER: Divo MJ 

PROVIDER: S-EPMC9516817 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature