Long-Term Effects of Ambient Particulate and Gaseous Pollutants on Serum High-Sensitivity C-Reactive Protein Levels: A Cross-Sectional Study Using KoGES-HEXA Data.

ABSTRACT: Ambient air pollutants reportedly increase inflammatory responses associated with multiple chronic diseases. We investigated the effects of long-term exposure to ambient air pollution on high-sensitivity C-reactive protein (hs-CRP) using data from 60,581 participants enrolled in the Korean Genome and Epidemiology Study-Health Examinees Study between 2012 and 2017. Community Multiscale Air Quality System with surface data assimilation was used to estimate the participants' exposure to criteria air pollutants based on geocoded residential addresses. Long-term exposure was defined as the 2-year moving average concentrations of PM₁₀, PM_2.5, SO₂, NO₂, and O₃. Multivariable linear and logistic regression models were utilized to estimate the

SUBMITTER: Kim JH 

PROVIDER: S-EPMC9517608 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature