Parasite burden and red blood cell exchange transfusion for babesiosis.

ABSTRACT:

Background

The association between parasite burden and end-organ dysfunction in subjects with Babesia microti infection has not been extensively studied, nor has the optimal role of red blood cell exchange (RCE) transfusion in babesiosis treatment. This retrospective chart review evaluates the associations between parasitemia, end-organ dysfunction, and outcomes in babesiosis patients treated with antimicrobial agents and RCE compared to those treated with antimicrobial agents alone.

Materials and methods

We evaluated adults (≥18 years of age) with laboratory-confirmed babesiosis who were admitted between 2011 and 2017 to Yale New Haven Hospital, located in a Babesia-endemic region of the Northeastern United States. Patient demographics, parasitemia levels, clinical and labo

SUBMITTER: O'Bryan J 

PROVIDER: S-EPMC9517950 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature