Network autonomic analysis of post-acute sequelae of COVID-19 and postural tachycardia syndrome.

ABSTRACT:

Background

The autonomic nervous system (ANS) is a complex network where sympathetic and parasympathetic domains interact inside and outside of the network. Correlation-based network analysis (NA) is a novel approach enabling the quantification of these interactions. The aim of this study is to assess the applicability of NA to assess relationships between autonomic, sensory, respiratory, cerebrovascular, and inflammatory markers on post-acute sequela of COVID-19 (PASC) and postural tachycardia syndrome (POTS).

Methods

In this retrospective study, datasets from PASC (n = 15), POTS (n = 15), and matched controls (n = 11) were analyzed. Networks were constructed from surveys (autonomic and sensory), autonomic tests (deep breathing, Valsalva maneuver, tilt, and sudomotor test)

SUBMITTER: Novak P 

PROVIDER: S-EPMC9517969 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature