Excellent Response to OnabotulinumtoxinA: Different Definitions, Different Predictors.

ABSTRACT: The identification of patients who can benefit the most from the available preventive treatments is important in chronic migraine. We explored the rate of excellent responders to onabotulinumtoxinA in a multicenter European study and explored the predictors of such response, according to different definitions. A pooled analysis on chronic migraineurs treated with onabotulinumtoxinA and followed-up for, at least, 9 months was performed. Excellent responders were defined either as patients with a ≥75% decrease in monthly headache days (percent-based excellent responders) or as patients with <4 monthly headache days (frequency-based excellent responders). The characteristics of excellent responders at the baseline were compared with the ones of patients with a <30% decrease in monthly h

SUBMITTER: Ornello R 

PROVIDER: S-EPMC9518492 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature