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Open vs minimally invasive radical trachelectomy in early-stage cervical cancer: International Radical Trachelectomy Assessment Study.


ABSTRACT:

Background

Minimally invasive radical trachelectomy has emerged as an alternative to open radical hysterectomy for patients with early-stage cervical cancer desiring future fertility. Recent data suggest worse oncologic outcomes after minimally invasive radical hysterectomy than after open radical hysterectomy in stage I cervical cancer.

Objective

We aimed to compare 4.5-year disease-free survival after open vs minimally invasive radical trachelectomy.

Study design

This was a collaborative, international retrospective study (International Radical Trachelectomy Assessment Study) of patients treated during 2005-2017 at 18 centers in 12 countries. Eligible patients had squamous carcinoma, adenocarcinoma, or adenosquamous carcinoma; had a preoperative tumor size of ≤2 cm;

SUBMITTER: Salvo G 

PROVIDER: S-EPMC9518841 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature