Agreement between nicotine metabolites in blood and self-reported smoking status: The Netherlands Epidemiology of Obesity study.

ABSTRACT:

Introduction

Self-report and nicotine detection are methods to measure smoking exposure and can both lead to misclassification. It is important to highlight discrepancies between these two methods in the context of epidemiological research.

Objective

The aim of this cross-sectional study is to assess the agreements between self-reported smoking status and nicotine metabolite detection.

Methods

Data of 599 participants from the Netherlands Epidemiology of Obesity study were used to compare serum metabolite levels of five nicotine metabolites (cotinine, hydroxy-cotinine, cotinine N-Oxide, norcotinine, 3-hydroxy-cotinine-glucuronide) between self-reported never smokers (n = 245), former smokers (n = 283) and current smokers (n = 71). We assessed whether metabolite

SUBMITTER: Folpmers S 

PROVIDER: S-EPMC9519471 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature