Ionizing radiation exposure during adulthood and risk of developing central nervous system tumors: systematic review and meta-analysis.

ABSTRACT: Many studies on ionizing radiation (IR) exposure during childhood have shown deleterious effects on the central nervous system (CNS), however results regarding adult exposure are inconsistent, and no systematic reviews have been performed. The objectives are to synthesize the findings and draw evidence-based conclusions from epidemiological studies on the risk of benign and malignant brain and CNS tumors in humans exposed to low-to-moderate doses (< 0.5 Gy) of IR during adulthood/young adulthood. A systematic literature search of four electronic databases, supplemented by a hand search, was performed to retrieve relevant epidemiological studies published from 2000 to 2022. Pooled excess relative risk (ERR_pooled) was estimated using a random effect model. Eighteen publications we

SUBMITTER: Lopes J 

PROVIDER: S-EPMC9519546 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature