[⁶⁸Ga]FAPI-PET/CT for radiation therapy planning in biliary tract, pancreatic ductal adeno-, and adenoidcystic carcinomas.

ABSTRACT: Biliary-tract-carcinomas (BTC), pancreatic-ductal-adenocarcinomas (PDAC) and adenoidcystic-carcinomas (AC) have in common that they are traditionally treated with large clinical-target-volumes (CTV). The aim of this study is to examine the impact of pretreatment-[⁶⁸Ga]FAPI-PET/CT on target-volume-definition and posttreatment-[⁶⁸Ga]FAPI-PET/CT-response-assessment for BTC-, PDAC- and AC-patients referred to radiation-therapy. All consecutive BTC-, PDAC-, and AC-patients who received pretreatment-[⁶⁸Ga]FAPI-PET/CT±[¹⁸F]FDG-PET/CT were included from 01.01.2020 to 01.03.2022. MTV and SUV_max were separately generated based on [⁶⁸Ga]FAPI- and [¹⁸F]FDG-PET/CT-images. A [⁶⁸Ga]FAPI- and [¹⁸F]FDG-based-

SUBMITTER: Guberina N 

PROVIDER: S-EPMC9519639 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature