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CFD simulation on optimum material to fabricate the counter flow of Ranque-Hilsch vortex tube.

ABSTRACT: The basic objective of the current investigation by using CFD simulation is to select the appropriate material to fabricate Vortex tubes in meteorological conditions, which can improve efficiency and performance. The simulation results of vortex tubes were used in obtaining the performance for various materials such as copper, stainlessteel, brass, PVC, CPVC, acrylic, nylon, and bronze. The ratio of length of the hot tube and inner diameter was chosen as (L/D) 40 with the consistent inner diameter of the hot tube as 15 mm. Compressed air is passed through an inlet pipe between 2 and 12 bars in the step of 2 bars. 2D CFD was developed and analyzed with Ansys Fluent to access the performance of the vortex tube. Finally, after evaluating all simulation values for eight materials for performance depending upon their physical properties varies in the sequence from copper-bronze-brass-stainless steel-CPVC-PVC-acrylic-nylon material.

SUBMITTER: Rao KKK

PROVIDER: S-EPMC9519905 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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CFD simulation on optimum material to fabricate the counter flow of Ranque-Hilsch vortex tube.

Rao K Kiran Kumar KKK Ramesh A A Hampali Chennabasappa C

Scientific reports 20220928 1

The basic objective of the current investigation by using CFD simulation is to select the appropriate material to fabricate Vortex tubes in meteorological conditions, which can improve efficiency and performance. The simulation results of vortex tubes were used in obtaining the performance for various materials such as copper, stainlessteel, brass, PVC, CPVC, acrylic, nylon, and bronze. The ratio of length of the hot tube and inner diameter was chosen as (L/D) 40 with the consistent inner diamet ...[more]

PMID: 36171240

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Project description:Polyglycolic acid (PGA) nanoparticles show promise in biomedical applications due to their exceptional biocompatibility and biodegradability. These nanoparticles can be readily modified, facilitating targeted drug delivery and promoting specific interactions with diseased tissues or cells, including imaging agents and theranostic approaches. Their potential to advance precision medicine and personalized treatments is evident. However, conventional methods such as emulsification solvent evaporation via batch synthesis or tubular reactors via flow chemistry have limitations in terms of nanoparticle properties, productivity, and scalability. To overcome these limitations, this study focuses on the design and development of a 3D-printed vortex tube reactor for the continuous synthesis of PGA nanoparticles using flow chemistry. Computer-aided design (CAD) and the design of experiments (DoE) optimize the reactor design, and computational fluid dynamics simulations (CFD) evaluate the mixing index (MI) and Reynolds (Re) expression. The optimized reactor design was fabricated using fused deposition modeling (FDM) with polypropylene (PP) as the polymer. Dispersion experiments validate the optimization process and investigate the impact of input flow parameters. PGA nanoparticles were synthesized and characterized for size and polydispersity index (PDI). The results demonstrate the feasibility of using a 3D-printed vortex tube reactor for the continuous synthesis of PGA nanoparticles through flow chemistry and highlight the importance of reactor design in nanoparticle production. The CFD results of the optimized reactor design showed homogeneous mixing across a wide range of flow rates with increasing Reynolds expression. The residence time distribution (RTD) results confirmed that increasing the flow rate in the 3D-printed vortex tube reactor system reduced the dispersion variance in the tracer. Both experiments demonstrated improved mixing efficiency and productivity compared to traditional tubular reactors. The study also revealed that the total flow rate had a significant impact on the size and polydispersity index of the formulated PGA nanoparticle, with the optimal total flow rate at 104.46 mL/min, leading to smaller nanoparticles and a lower polydispersity index. Additionally, increasing the aqueous-to-organic volumetric ratio had a significant effect on the reduced particle size of the PGA nanoparticles. Overall, this study provides insights into the use of 3D-printed vortex tube reactors for the continuous synthesis of PGA nanoparticles and underscores the importance of reactor design and flow parameters in PGA nanoparticle formulation.

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CFD simulation on optimum material to fabricate the counter flow of Ranque-Hilsch vortex tube.

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CFD simulation on optimum material to fabricate the counter flow of Ranque-Hilsch vortex tube.

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