Racial and ethnic differences in pharmacotherapy to prevent coronary artery disease and thrombotic events.

ABSTRACT: Awareness of racial/ethnic disparities represents a key challenge for healthcare systems that attempt to provide effective healthcare and to reduce existing inequalities in the use of and adherence to guideline-recommended cardiovascular drugs to improve clinical outcomes for cardiovascular disease (CVD). In this review, we describe important racial/ethnic differences between and within ethnic groups in the prevalence, risk factors, haemostatic factors, anti-inflammatory and endothelial markers, recurrence, and outcomes of CVD. We discuss important differences in the selection, doses, and response [efficacy and adverse drug reactions (ADRs)] in ethnically diverse patients treated with antithrombotics or lipid-lowering drugs. Differences in drug response are mainly related to racial/ethnic

SUBMITTER: Tamargo J 

PROVIDER: S-EPMC9520447 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature