Magnetic Resonance Imaging-targeted Prostate Biopsy Compared with Systematic Prostate Biopsy in Biopsy-naive Patients with Suspected Prostate Cancer.

ABSTRACT:

Background

It remains uncertain whether transrectal ultrasound (TRUS)-guided systematic biopsies can be omitted and rely solely on multiparametric magnetic resonance imaging-targeted biopsies (MRI-TBx) in biopsy-naïve men suspected of prostate cancer (PCa).

Objective

To compare PCa detection in biopsy-naïve men between systematic biopsy and MRI-TBx.

Design setting and participants

A prospective cohort study was conducted in a Dutch teaching hospital. Consecutive patients with suspected PCa, no history of biopsy, and no clinical suspicion of metastasis underwent both TRUS-guided systematic biopsies and MRI-TBx by multiparametric magnetic resonance imaging (mpMRI)-ultrasound fusion, including sham biopsies in case of negative mpMRI.

Outcome measurements and statistic

SUBMITTER: Alkema NG 

PROVIDER: S-EPMC9520499 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature