Assessment of genotypes, endosymbionts and clinical characteristics of Acanthamoeba recovered from ocular infection.

ABSTRACT:

Introduction

Acanthamoeba is an emerging pathogen, infamous for its resilience against antiprotozoal compounds, disinfectants and harsh environments. It is known to cause keratitis, a sight-threatening, painful and difficult to treat corneal infection which is often reported among contact lens wearers and patients with ocular trauma. Acanthamoeba comprises over 24 species and currently 23 genotypes (T1-T23) have been identified.

Aims

This retrospective study was designed to examine the Acanthamoeba species and genotypes recovered from patients with Acanthamoeba keratitis (AK), determine the presence of endosymbionts in ocular isolates of Acanthamoeba and review the clinical presentations.

Methodology

Thirteen culture-confirmed AK patients treated in a tertiary eye car

SUBMITTER: Rayamajhee B 

PROVIDER: S-EPMC9520893 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature