Replication of a synthetic oligomer using chameleon base-pairs.

ABSTRACT: Salt bridges were used to attach polymerisable amidine monomers to an oligomeric benzoic acid template. CuAAC oligomerisation reactions in the presence of a benzoic acid 3-mer template gave the amidine 3-mer copy as the major product. Cleavage of ester linkers was used to hydrolyse off the amidine recognition units and convert the product into a benzoic acid 3-mer copy of the original template.

SUBMITTER: Nunez-Villanueva D 

PROVIDER: S-EPMC9521413 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature