Delayed improvements in visual memory task performance among chronic schizophrenia patients after high-frequency repetitive transcranial magnetic stimulation.

ABSTRACT:

Background

Cognitive impairments are core characteristics of schizophrenia, but are largely resistant to current treatments. Several recent studies have shown that high-frequency repetitive transcranial magnetic stimulation (rTMS) of the left dor-solateral prefrontal cortex (DLPFC) can reduce negative symptoms and improve certain cognitive deficits in schizophrenia patients. However, results are inconsistent across studies.

Aim

To examine if high-frequency rTMS of the DLPFC can improve visual memory deficits in patients with schizophrenia.

Methods

Forty-seven chronic schizophrenia patients with severe negative symptoms on stable treatment regimens were randomly assigned to receive active rTMS to the DLPFC (n = 25) or sham stimulation (n = 22) on weekdays

SUBMITTER: Du XD 

PROVIDER: S-EPMC9521529 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature