Automatic curation of LTR retrotransposon libraries from plant genomes through machine learning.

ABSTRACT: Transposable elements are mobile sequences that can move and insert themselves into chromosomes, activating under internal or external stimuli, giving the organism the ability to adapt to the environment. Annotating transposable elements in genomic data is currently considered a crucial task to understand key aspects of organisms such as phenotype variability, species evolution, and genome size, among others. Because of the way they replicate, LTR retrotransposons are the most common transposable elements in plants, accounting in some cases for up to 80% of all DNA information. To annotate these elements, a reference library is usually created, a curation process is performed, eliminating TE fragments and false positives and then annotated in the genome using the homology method. However,

SUBMITTER: Orozco-Arias S 

PROVIDER: S-EPMC9521825 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature