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The Diagnostic Accuracy of Chest Radiographic Features for Pediatric Intrathoracic Tuberculosis.


ABSTRACT:

Introduction

The chest radiograph (CR) remains a key tool in the diagnosis of pediatric tuberculosis (TB). In children with presumptive intrathoracic TB, we aimed to identify CR features that had high specificity for, and were strongly associated with, bacteriologically confirmed TB.

Methods

We analyzed CR data from children with presumptive intrathoracic TB prospectively enrolled in a cohort study in a high-TB burden setting and who were classified using standard clinical case definitions as "confirmed," "unconfirmed," or "unlikely" TB. We report the CR features and inter-reader agreement between expert readers who interpreted the CRs. We calculated the sensitivity and specificity of the CR features with at least moderate inter-reader agreement and analyzed the relationship

SUBMITTER: Palmer M 

PROVIDER: S-EPMC9522424 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature