Aberrant gray matter volume and functional connectivity in Parkinson's disease with minor hallucination.

ABSTRACT:

Background

Minor hallucination (MH) is the most common psychotic symptom in Parkinson's disease (PD); it can develop into well-structured visual hallucination (VH), suggesting that MH may be a staccato form of well-structured VH. However, it remains unclear whether the pathogenesis is the same. Therefore, the aim of this study was to investigate the altered gray matter volume (GMV) and functional connectivity (FC) of MH in PD to further understand the complex mechanisms.

Materials and methods

We included 67 PD patients who attended the outpatient clinic of Nanjing Medical University Affiliated Brain Hospital and recruited 31 healthy controls (HC). Demographic data and clinical characteristics of all subjects were recorded, and cranial structural magnetic resonance imaging (M

SUBMITTER: Zhong M 

PROVIDER: S-EPMC9522711 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature