Exercise and Exercise Mimetics for the Treatment of Musculoskeletal Disorders.

ABSTRACT:

Purpose of review

The incidence of musculoskeletal disorders affecting bones, joints, and muscles is dramatically increasing in parallel with the increased longevity of the worldwide population, severely impacting on the individual's quality of life and on the healthcare costs. Inactivity and sedentary lifestyle are nowadays considered the main drivers of age-associated musculoskeletal disorders and exercise may counteract such alterations also in other bone- and muscle-centered disorders. This review aims at clarifying the potential use of exercise training to improve musculoskeletal health.

Recent findings

Both the skeletal muscle and the bone are involved in a complex crosstalk determining, in part through tissue-specific and inflammatory/immune released factors, the occu

SUBMITTER: Cento AS 

PROVIDER: S-EPMC9522759 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature