A functional neuroimaging study of self-other processing alterations in atypical developmental trajectories of psychotic-like experiences.

ABSTRACT: Self-disturbances constitute a hallmark of psychosis, but it remains unclear whether these alterations are present in at-risk populations, and therefore their role in the development of psychosis has yet to be confirmed. The present study addressed this question by measuring neural correlates of self-other processing in youth belonging to three developmental trajectories of psychotic experiences. Eighty-six youths were recruited from a longitudinal cohort of over 3800 adolescents based on their trajectories of Psychotic-Like Experiences from 12 to 16 years of age. Participants underwent neuroimaging at 17 years of age (mean). A functional neuroimaging task evaluating self- and other-related trait judgments was used to measure whole-brain activation and connectivity. Youth who showed an inc

SUBMITTER: Assaf R 

PROVIDER: S-EPMC9522794 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature