The dual neural effects of oxytocin in autistic youth: results from a randomized trial.

ABSTRACT: Recent discoveries have highlighted the effects of oxytocin (OT) on social behavior and perception among autistic individuals. However, a gap persists in the literature regarding the potential effects of OT and the neural temporal dynamics due to OT administration. We explored the effect of OT on autistic individuals using magnetoencephalography (MEG), focusing on M100, M170, and M250, social perception-related components that tend to show atypical patterns in autistic individuals. Twenty-five autistic adolescents participated in this randomized, double-blind MEG study. Autistic individuals arrived at the lab twice and received an acute dose of intranasal OT or placebo in each session. During the scans, participants were asked to identify pictures of social and non-social stimuli. Addition

SUBMITTER: Korisky A 

PROVIDER: S-EPMC9523043 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature