¹⁸F-NaF PET/MRI for Detection of Carotid Atheroma in Acute Neurovascular Syndrome.

ABSTRACT: Background MRI and fluorine 18-labeled sodium fluoride (¹⁸F-NaF) PET can be used to identify features of plaque instability, rupture, and disease activity, but large studies have not been performed. Purpose To evaluate the association between ¹⁸F-NaF activity and culprit carotid plaque in acute neurovascular syndrome. Materials and Methods In this prospective observational cohort study (October 2017 to January 2020), participants underwent ¹⁸F-NaF PET/MRI. An experienced clinician determined the culprit carotid artery based on symptoms and record review. ¹⁸F-NaF uptake was quantified using standardized uptake values and tissue-to-background ratios. Statistical significance was assessed with the Welch, χ², Wilcoxon, or Fisher test. Mult

SUBMITTER: Kaczynski J 

PROVIDER: S-EPMC9523682 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature