Associations of habitual glucosamine supplementation with incident gout: a large population based cohort study

ABSTRACT:

Objectives

The association between habitual glucosamine use and incident gout has not been examined in previous studies. We aimed to evaluate the association of habitual use of glucosamine with the risk of gout in general population.

Methods

A total of 436,594 participants (55.4% female) without prior gout at baseline who completed a questionnaire on supplementation use, which included glucosamine, in the UK Biobank were enrolled. Incident gout was recorded from self-report, death register, primary care, and hospital admission data.

Results

At baseline, 53,433 (22.1%) females and 30,685 (15.8%) males reported habitual glucosamine use. During a median follow-up period of 12.1 years, 1718 (0.7%) females and 5685 (2.9%) males developed gout. After multivariable adju

SUBMITTER: Liu M 

PROVIDER: S-EPMC9524004 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature