Cytokine-polymorphisms associated with Preeclampsia: A review.

ABSTRACT:

Background

Preeclampsia (PE) is a syndromic disorder that affects 2% to 8% of pregnancies and is diagnosed principally when hypertension appears in the second-d half of pregnancy. WHO estimates the incidence of PE to be seven times higher in developing countries than in developed countries. Severe preeclampsia/eclampsia is one of the most important causes of maternal mortality, associated with 50,000 to 100,000 annual deaths globally as well as serious fetal and neonatal morbidity and mortality, especially in developing countries. Even though evidence from family-based studies suggest PE has a heritable component, its etiology, and specific genetic contributions remain unclear. Many studies examining the genetic factors contributing to PE have been conducted, most of them are focus

SUBMITTER: Mora-Palazuelos C 

PROVIDER: S-EPMC9524891 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature