Brown algae and barley-based anti-obesity food and its safety in C57BL6 mice.

ABSTRACT: Brown algae have been considered a potential source of bioactives and used as a dietary supplement to manage obesity and its associated health complications. However, its effective use is limited due to heavy metals and microbial contamination, unawareness of health benefits and limited dietary exploitation. We developed, the Indian brown algae Padina tetrastromatica and barley-based anti-obesity food (AOF) and examined for microbial and heavy metal safety. Additionally, acute [0 (control), 50, 100, 200, 500 g AOF/kg diet] and sub-acute [0, 5, 50 g AOF/kg diet] doses of AOF were fed to C57BL6 mice and toxicity was examined. The physical, locomotory, hematological, biochemical parameters and histopathology were examined. Postprandial plasma and tissue levels of fucoxanthin and its me

SUBMITTER: Sharma PP 

PROVIDER: S-EPMC9525497 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature