Genomics analysis of Drosophila sechellia response to Morinda citrifolia fruit diet.

ABSTRACT: Drosophila sechellia is an island endemic host specialist that has evolved to consume the toxic fruit of Morinda citrifolia, also known as noni fruit. Recent studies by our group and others have examined genome-wide gene expression responses of fruit flies to individual highly abundant compounds found in noni responsible for the fruit's unique chemistry and toxicity. In order to relate these reductionist experiments to the gene expression responses to feeding on noni fruit itself, we fed rotten noni fruit to adult female D. sechellia and performed RNA-sequencing. Combining the reductionist and more wholistic approaches, we have identified candidate genes that may contribute to each individual compound and those that play a more general role in response to the fruit as a whole. Using the co

SUBMITTER: Drum Z 

PROVIDER: S-EPMC9526069 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature