Temporal Changes in Cholangiocarcinoma Incidence and Mortality in the United States from 2001 to 2017.

ABSTRACT:

Background

Previous studies report increasing cholangiocarcinoma (CCA) incidence up to 2015. This contemporary retrospective analysis of CCA incidence and mortality in the US from 2001-2017 assessed whether CCA incidence continued to increase beyond 2015.

Patients and methods

Patients (≥18 years) with CCA were identified in the National Cancer Institute Surveillance, Epidemiology, and End Results 18 cancer registry (International Classification of Disease for Oncology [ICD-O]-3 codes: intrahepatic [iCCA], C221; extrahepatic [eCCA], C240, C241, C249). Cancer of unknown primary (CUP) cases were identified (ICD-O-3: C809; 8140/2, 8140/3, 8141/3, 8143/3, 8147/3) because of potential misclassification as iCCA.

Results

Forty-thousand-and-thirty CCA cases (iCCA, n=13,174; eC

SUBMITTER: Javle M 

PROVIDER: S-EPMC9526482 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature