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Systems Network Pharmacology-Based Prediction and Analysis of Potential Targets and Pharmacological Mechanism of Actinidia chinensis Planch. Root Extract for Application in Hepatocellular Carcinoma.

ABSTRACT:

SUBMITTER: Hu Y

PROVIDER: S-EPMC9526650 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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Systems Network Pharmacology-Based Prediction and Analysis of Potential Targets and Pharmacological Mechanism of Actinidia chinensis Planch. Root Extract for Application in Hepatocellular Carcinoma.

Hu Yue Y Yang Liang L Lu Yunfei Y Wang Yong Y Jiang Jianshuai J Liu Yahui Y Cao Qing Q

Evidence-based complementary and alternative medicine : eCAM 20220920

<h4>Purpose</h4>Traditional Chinese medicine (TCM) sometimes plays a crucial role in advanced cancer treatment. Despite the significant therapeutic efficacy in hepatocellular carcinoma (HCC) that Actinidia chinensis Planch root extract (acRoots) has proven, its complex composition and underlying mechanism have not been fully elucidated. Therefore, this study analyzed the multiple chemical compounds in acRoots and their targets via network pharmacology and bioinformatics analysis, with the ...[more]

PMID: 36193154

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