A manually curated compendium of expression profiles for the microbial cell factory Corynebacterium glutamicum.

ABSTRACT: Corynebacterium glutamicum is the major host for the industrial production of amino acids and has become one of the best studied model organisms in microbial biotechnology. Rational strain construction has led to an improvement of producer strains and to a variety of novel producer strains with a broad substrate and product spectrum. A key factor for the success of these approaches is detailed knowledge of transcriptional regulation in C. glutamicum. Here, we present a large compendium of 927 manually curated microarray-based transcriptional profiles for wild-type and engineered strains detecting genome-wide expression changes of the 3,047 annotated genes in response to various environmental conditions or in response to genetic modifications. The replicates within the 927 experiments were

SUBMITTER: Kranz A 

PROVIDER: S-EPMC9526701 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature