Association of Placental Pathology With Childhood Blood Pressure Among Children Born Preterm.

ABSTRACT:

Background

The in utero pathologies underlying the link between preterm birth and offspring high blood pressure (BP) are still unknown. We investigated the prospective associations of placental histopathological findings with childhood BP among children born preterm.

Methods

Our study sample included 546 mother-child pairs with preterm birth (before 37 weeks gestation) enrolled from 1999 to 2013 at the Boston Medical Center. Early preterm birth was defined as gestational age between 23 and 34 weeks. We histologically classified maternal placental pathology using the latest recommended categories: no placental complications, histologic chorioamnionitis, maternal vascular malperfusion, and other placental complications. We calculated age-, sex-, and height-specific systolic BP

SUBMITTER: Long J 

PROVIDER: S-EPMC9526806 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature