Research race-specific reference values and lung function impairment, breathlessness and prognosis: Analysis of NHANES 2007-2012.

ABSTRACT:

Background

Spirometry reference values differ by race/ethnicity, which is controversial. We evaluated the effect of race-specific references on prevalence of lung function impairment and its relation to breathlessness and mortality in the US population.

Methods

Population-based analysis of the National Health and Nutrition Examination Survey (NHANES) 2007-2012. Race/ethnicity was analyzed as black, white, or other. Reference values for forced expiratory volume in one second (FEV₁) and forced vital capacity (FVC) were calculated for each person using the Global Lung Initiative (GLI)-2012 equations for (1) white; (2) black; and (3) other/mixed people. Outcomes were prevalence of lung function impairment (< lower limit of normal [LLN]), moderate/severe impairment (< 

SUBMITTER: Ekstrom M 

PROVIDER: S-EPMC9526909 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature