Preconception vitamin D and miscarriage in a prospective cohort study.

ABSTRACT:

Study question

Is preconception vitamin D level associated with the risk of miscarriage?

Summary answer

Preconception vitamin D levels are not associated with the risk of miscarriage in a population of women conceiving naturally.

What is known already

In humans, low vitamin D has been associated with prolonged menstrual cycles, delayed ovulation and a lower probability of conception. Animal and in vitro data indicate that vitamin D may affect implantation.

Study design, size, duration

This prospective time-to-pregnancy study included 362 women who were trying to conceive naturally between 2008 and 2015.

Participants/materials, setting, methods

This study included participants who had been trying to conceive naturally for 3 months or less at enrollment an

SUBMITTER: Subramanian A 

PROVIDER: S-EPMC9527460 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature