A Randomized Controlled Pilot Study of Topical Ropivacaine for Prevention of Post-POEM Pain.

ABSTRACT:

Background and aims

Although usually mild to moderate in severity, postoperative pain after peroral endoscopic myotomy (POEM) is common. There are no studies that have addressed minimizing postoperative pain in patients undergoing POEM for achalasia. We hypothesized that intraoperative topical intra-tunnel irrigation with ropivacaine would result in a significant reduction in pain scores in the postoperative period.

Methods

A double-blind, randomized, placebo-controlled trial was conducted at the Kingston Health Sciences Center. Patients received either 30 mL of 0.2% ropivacaine or 30 mL of placebo irrigated topically into the POEM tunnel after completing the myotomy and prior to closing the mucosal incision. The primary outcome was pain post-POEM at 6 h assessed by the Nume

SUBMITTER: Rai M 

PROVIDER: S-EPMC9527655 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature