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Mayaro as a Caribbean traveler: Evidence for multiple introductions and transmission of the virus into Haiti.

ABSTRACT: Mayaro virus (MAYV) is a mosquito-transmitted alphavirus that is being recognized with increasing frequency in South America. As part of on-going surveillance of a school cohort in Haiti, we identified MAYV infections in 5 children across a 7-month time span, at two different school campuses. All had a history of fever, and three had headaches; none complained of arthralgias. On analysis of whole genome sequence data, three strains were genotype D, and two were genotype L; phylogenetic and molecular clock analysis was consistent with at least 3 independent introductions of the virus into Haiti, with ongoing transmission of a common genotype D strain in a single school. Our data highlight the clear potential for spread of the virus in the northern Caribbean and North America.

SUBMITTER: Blohm G

PROVIDER: S-EPMC9527705 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature

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Mayaro as a Caribbean traveler: Evidence for multiple introductions and transmission of the virus into Haiti.

Blohm Gabriela G Elbadry Maha A MA Mavian Carla C Stephenson Caroline C Loeb Julia J White Sarah S Telisma Taina T Chavannes Sonese S Beau De Rochar Valerie Madsen VM Salemi Marco M Lednicky John A JA Morris J Glenn JG

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20190802

Mayaro virus (MAYV) is a mosquito-transmitted alphavirus that is being recognized with increasing frequency in South America. As part of on-going surveillance of a school cohort in Haiti, we identified MAYV infections in 5 children across a 7-month time span, at two different school campuses. All had a history of fever, and three had headaches; none complained of arthralgias. On analysis of whole genome sequence data, three strains were genotype D, and two were genotype L; phylogenetic and molec ...[more]

PMID: 31382049

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Dataset Information

Mayaro as a Caribbean traveler: Evidence for multiple introductions and transmission of the virus into Haiti.

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Mayaro as a Caribbean traveler: Evidence for multiple introductions and transmission of the virus into Haiti.

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