Fetal and Childhood Exposure to Parental Tobacco Smoking and Arterial Health at Age 10 Years.

ABSTRACT:

Background

Exposure to parental tobacco smoking during fetal life and childhood is associated with adverse cardiovascular health outcomes. It is not known whether these adverse parental lifestyle exposures are also associated with changes in the structure and function of the carotid arteries in children aged 10 years.

Methods

In a population-based prospective cohort study among 4,639 healthy children, we examined the associations of fetal exposure to maternal (no, first trimester only, continued), paternal (no, yes), and combined parental tobacco smoking (nonsmoking parents, mother only, father only, both parents smoked) with carotid intima-media thickness and distensibility at 10 years. We also assessed the associations of exposure to any parental tobacco smoking at ages 6

SUBMITTER: Monasso GS 

PROVIDER: S-EPMC9527773 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature