Characterization of serum protein expression profiles in the early sarcopenia older adults with low grip strength: a cross-sectional study.

ABSTRACT:

Background

Sarcopenia refers to the progressive loss of skeletal muscle mass and muscle function, which seriously threatens the quality of life of the older adults. Therefore, early diagnosis is urgently needed. This study aimed to explore the changes of serum protein profiles in sarcopenia patients through a cross-sectional study, and to provide the reference for clinical diagnosis.

Methods

This study was a cross-sectional study carried out in the Tianjin institute of physical education teaching experiment training center from December 2019 to December 2020. Ten older adults were recruited, including 5 sarcopenia and 5 healthy older adults. After a detailed diagnostic evaluation, blood samples were collected to prepare serum for proteomic analysis using the HPLC System Easy

SUBMITTER: Wu J 

PROVIDER: S-EPMC9528053 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature