MicroRNA-21 as a potential biomarker for detecting esophageal carcinoma in Asian populations: a meta-analysis.

ABSTRACT:

Background

MicroRNA-21 (miR-21) is significantly expressed in a variety of cancers and could be used as a tumor biomarker. However, the results are varied, and no studies on the diagnostic usefulness of miR-21 in Asian esophageal cancer (EC) patients have been published. This meta-analysis was aimed at exploring whether miR-21 can be used as a diagnostic marker and assessing its effectiveness.

Methods

The relevant literature was identified in six main databases: Ovid MEDLINE, PsycINFO, PubMed MEDLINE, Embase, Web of Science, and the Cochrane Library. Two researchers independently selected the literature based on the inclusion and exclusion criteria, extracted data, and evaluated the risk of bias. The meta-analysis was carried out using Review Manager 5.4, Meta-Disc 1.4 and S

SUBMITTER: Han Z 

PROVIDER: S-EPMC9528905 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature