Effects of Empagliflozin in Women and Men With Heart Failure and Preserved Ejection Fraction.

ABSTRACT:

Background

Women and men with heart failure (HF) and preserved ejection fraction may differ in their clinical characteristics and their response to therapy. The aim of this study was to evaluate the influence of sex on the effects of empagliflozin in patients with HF and preserved ejection fraction enrolled in the EMPEROR-Preserved trial (Empagliflozin Outcome Trial in Patients With Chronic Heart Failure With Preserved Ejection Fraction).

Methods

The effects of empagliflozin on the primary outcome of cardiovascular death or hospitalization for HF and on secondary outcomes (including total HF hospitalization, cardiovascular and all-cause mortality, and Kansas City Cardiomyopathy Questionnaire scores) were compared in women and men in the overall cohort and in subgroups define

SUBMITTER: Butler J 

PROVIDER: S-EPMC9528945 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature